How healing happens after a soft-tissue Injury

There are 3 key stages: (1) Acute Inflammation (2) Post Acute RepaIr/ Proliferation (3) Remodelling

(1) Acute Inflammation (after injury, hematoma formation)
Usually 1-2 days, up to 5 days (depends on tissue & severity of injury)
Cardinal Signs – Swelling, Heat, A loss of function, Redness, & Pain (chemical irritation & nerve pressure) may not reach peak until 5-7 days post injury.

(2) Post Acute Repair/ Proliferation (scar tissue formation)
48 hours up to 6+ weeks. Involves synthesis & deposition of collagen; macrophages/phagocytes remove cell debris, erythrocytes, & fibrin clot. Collagen is not oriented in direction of tensile strenath & quality is inferior to original

(3) Remodelling (fibroblastic activity & fibrosis)
3 weeks to 12+ months. Collagen is remodeled to increase the functional capabilities of the tissue in the direction of stresses imposed upon it (PFROM/stretching help re-establish strength). New collagen forms which increases tensile strength of wounds. Scar tissue is ~80% as strong as original tissue & residual fibrosis is common

Vizniak(2015)